July was Kamila's last month at OIST. Best of luck in the next stage of her career!
Keisuke's PD-SELEX paper
is now online on Nucleic Acids Research as a "Breakthrough Article".
Welcome to another new postdoc Marius!
Welcome to our new postdoc Lara who joined our unit as a JSPS fellow!
Welcome to Fernanda and Samira who will be rotating in our unit through August.
Congratulations to Gear his JSPS predoctoral fellowship (DC2)!
Proud to introduce Dr. Kamila Mustafina, the first Ph.D. from the Nucleic Acid Chemistry and Engineering Unit. Congratulations!
We miss our virologist Kei who has moved on to his next position at MIT!
Conglatulations to Samuel for being awarded a Walter Benjamin fellowship from DFG!
A review article highlighting sequencing-based assay of ribozymes and deoxyribozymes is now online at Accounts of Chemical Research
Welcome to Nao who has started as a new technician. 4/1/2020
Congratulations to Narae for her KAKENHI grant!
We welcome two new members at the start of the new year! Arriving with a fresh Ph.D. from Germany, Samuel is our new microbiologist. Shiv is our new research intern from the UK who will work with us for about six months.
Congratulations to Kamila for her first paper published in ACS Synthetic Biology
!. With some help from Keisuke, she engineered and analyzed the tandem aptamer-ribozyme fusion architecture as mammalian riboswitches.
Mohammed's histamine aptamer was turned into a sensor for detecting food poisoning (published in Scientific Reports
Yatzu started her first rotation with us. Welcome!
Yohei coedited the annual Synthetic Biology section in Current Opinion in Chemical Biology
with Prof. Hirohide Saito at Kyoto University, focusing on mammalian synthetic biology. Check out 9 reviews including one on mammalian riboswitches
written by Yohei.
Yoko's work on minimizing an RNA ligase ribozyme using deep sequencing is now online in Nucleic Acids Research
. Such small ribozymes may resemble ancient catalysts in the RNA world.
Good luck to Laura who is leaving Okinawa to pursue her Ph.D. in Europe.
Kei's paper on using a riboswitch to control vesicular stomatitus virus (VSV) vector is now published in ACS Synthetic Biology
in which he demonstrated multiple cycles of ON/OFF gene regulation up to 12 days.
Welcome to our new technician, Mayumi.
Mohammed's work on histamine-responsive riboswitch and artificial cells is published in Journal of the American Chemical Society
(see OIST press release
). This was a great collaboration with the Matsuura group
at Osaka University who prepared and characterized beautiful liposomes containing our riboswitch!
Farewell to Mohammed and Dhamodharan, two of the original members of our Unit at OIST. Best of luck to both!
Shungo and Yoko's work on RNA molecular machine published in Nucleic Acids Research
. Covered in an OIST news story
with a cute artwork.
New JSPS KAKENHI grants awarded to Keisuke, Kei, Mohammed, Yoko, and Yohei.
Welcome to our new postdoc Vyankat Sontakke!
Goodbye and good luck to Kinuko who completed her internship and returned to Tokyo to finish her Ph.D.!
Yohei wrote a short review on applications of high-throughput sequencing to ribozyme investigations in Methods
Mohammed's new paper in ACS Synthetic Biology
demonstrates an exceptional ON/OFF ratio (3900) of gene expression by amplifying riboswitch response.
Welcome to Kinuko, a research intern from Tokyo who will be working with us for two months.
Welcome back to Gear who will start his thesis project in our unit!
We were awarded a JSPS Challenging Research (Exploratory) grant to develop chemically responsive artificial cells.
Dhamodharan (with Yoko and Mohammed) synthesized a photocaged guanine to control gene expression by light. The paper is now online at Chemical Communications
Keisuke joins as a new postdoc, and Aleksandra will spend this term in our unit as a rotation student!
Shungo's work on HDV-like ribozyme is now online at ACS Synthetic Biology
New Year brings new members
to the lab. Takeshi starts his thesis research, Bidesh rotates with us for the term, Keisuke from Osaka University starts his 9-week internship, and Narae joins as a new postdoc.